laboratory diagnostic - coagulation - 'profile THROMBOPHILIA I, including 6 parameters: Antithrombin III, activity + Protein C, activity + Protein S, activity + Activated protein C resistance + Factor V Leiden, mutation p.Arg506Gln + Factor II, Prothrombin, mutation G20210G>A (thrombophilia risk),for Factor V Leiden, mutation and Factor II, mutation - 5ml EDTA whole blood at room temperature for each test; for Antithrombin, Protein C, Protein S, Activated Protein C resistance - 1ml citrated plasma for each test, The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container. Protein C and Protein S are vitamin K dependant and testing must be perform well after any anti-vitamin K treatment (1 month). Attach the clinical data relating to the patient (major inflammatory syndrome, pregnancy, etc.) and the circumstances (bleeding, thrombosis, preoperative evaluation, etc.), Chromogenic method, ISO 15189, todylaboratories®, bmn, code L16LD1530

laboratory diagnostic - coagulation - 'profile THROMBOPHILIA II, including 7 parameters: Antithrombin III, activity + Protein C, activity + Protein S, activity + Activated protein C resistance + Factor V Leiden, mutation p.Arg506Gln + Factor II, Prothrombin, mutation G20210G>A + MTHFR gene mutation c.677C>T (thrombophilia risk),for Factor V Leiden mutation, Factor II mutation and gene MTHFR mutation - 5ml EDTA whole blood at room temperature for each test; for Antithrombin, Protein C, Protein S, Activated Protein C resistance - 1ml citrated plasma for each test, The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container. Protein C and Protein S are vitamin K dependant and testing must be perform well after any anti-vitamin K treatment (1 month). Attach the clinical data relating to the patient (major inflammatory syndrome, pregnancy, etc.) and the circumstances (bleeding, thrombosis, preoperative evaluation, etc.), Chromogenic method, ISO 15189, todylaboratories®, bmn, code L16LD1531

laboratory diagnostic - coagulation - 'profile THROMBOPHILIA screening, including 6 parameters: Antithrombin III, activity + Protein C, activity + Protein S, activity + Activated protein C resistance + Circulating anticoagulant (lupus anticoagulant) + Homocysteine, for Homocysteine - EDTA plasma 1 ml, The plasma must be frozen within 4 hour after collection and must be sent in the frozen samples container; for Antithrombin, Protein C, Protein S, Activated Protein C resistance - 1ml citrated plasma for each test, The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container. Protein C and Protein S are vitamin K dependant and testing must be perform well after any anti-vitamin K treatment (1 month). Attach the clinical data relating to the patient (major inflammatory syndrome, pregnancy, etc.) and the circumstances (bleeding, thrombosis, preoperative evaluation, etc.); for Circulating anticoagulant (lupus anticoagulant) - citrated plasma 2 ml, The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container, Chromogenic method, ISO 15189, todylaboratories®, code L16LD1532

laboratory diagnostic - coagulation - Activated protein C resistance, citrated plasma 2ml. The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container, 5 ml EDTA whole blood should also be sent for factor V Leiden testing by PCR in the case of a positive or a borderline activated protein C result. Please indicate if this test should be performed. It is advisable to send a frozen and centrifuged citrate sample in compliance with the GEHT pre-analytical recommendations. Factor V Leiden testing by PCR requires a signed consent form. Please attach clinical data and signed patient consent form, Chronometric, ISO 15189, todylaboratories®, bmn, code L16LD1581

laboratory diagnostic - coagulation - Anti-platelet antibodies bound and free, screening and identification - autoimmune thrombocytopenic purpura with severe thrombocytopenia, neonatal alloimmune thrombocytopenia, post-transfusion thrombocytopenia, for BOUND antibodies - EDTA whole blood 15ml at ambient temperature, IMPORTANT : if platelets < 20 giga/L, collect 40 mL of EDTA whole blood, but the test is difficult to perform. for FREE antibodies - serum 5ml refrigerated, Flow Cytometry/Immunocapture, ISO 15189, todylaboratories®, bmn, code L16LD1538

laboratory diagnostic - coagulation - Antithrombin - antigen, citrated plasma 1ml, The plasma must be frozen within 4 hour after collection and must be sent in the frozen samples container, Nephelometry, ISO 15189, todylaboratories®, bmn, code L16LD1537

laboratory diagnostic - coagulation - Antithrombin - functional activity, Citrated Plasma 1ml, Specify the treatment and circumstances of the request. The score is not cumulable with that of antithrombin antigen. Non-fractionated heparin may result in a moderate decrease; this is lower with LMWH. In the event of treatment, the assay may be performed. A deficiency is eliminated if the antithrombin is normal; in the event of a lowered result, a follow-up test will be requested excluding any treatment. In the case of an emergency, the family investigation may provide presumptive diagnostic assistance 1 specific aliquot for this analysis. The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container, Chromogenic, ISO 15189, todylaboratories®, bmn, code L16LD1536

laboratory diagnostic - coagulation - APTT (Activated Partial Thromboplastin Time), citrated plasma 2ml. It is advisable to send a frozen and centrifuged citrate sample in compliance with the GEHT pre-analytical recommendations. If possible, please specify if the patient is on an anticoagulant treatment as well as the clinical context. In the case of a request for aPTT without further precision, the following will be performed: FVIII, IX, XI, XII and lupus anticoagulant, The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container, Chronometric method, ISO 15189, todylaboratories®, bmn, code L16LD1539

laboratory diagnostic - coagulation - Circulating anticoagulant - lupus anticoagulant, citrated plasma 2ml. Sample to be frozen within 1 hour. Home sampling is not advisable. 1 specific aliquot for this analysis. Plasma with platelets removed by double centrifugation: 2500 g 15 min and settled plasma. The patient must not receive heparin. It is advisable to send a frozen and centrifuged citrate sample in compliance with the GEHT pre-analytical recommendations. It is advisable to collect the sample a while after any heparin treatment (NFH, LMWH, sodium danaparoid and rivaroxaban) During AVK treatment, lupus anticoagulant screening is possible up to an INR result of 3-3.5. The full test which includes the Rosner index and the dRVVT are systematically performed. The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container, Chronometric-F, ISO 15189, todylaboratories®, bmn, code L16LD1534

laboratory diagnostic - coagulation - D-Dimers, citrated plasma 1ml. It is advisable to send a frozen and centrifuged citrate sample in compliance with the GEHT pre-analytical recommendations (1 specific aliquot for this analysis). The plasma must be frozen within 4 hour after collection and must be sent in the frozen samples container, EIA or Immunoturbidimetry , ISO 15189, todylaboratories®, bmn, code L16LD1543

laboratory diagnostic - coagulation - Factor II - Prothrombin - G20210G>A mutation - thrombophilia risk, EDTA whole blood 5ml at ambient temperature. NOT FROZEN!!! Sample must be refrigerated if transport is > 48 hours. Please attach clinical data and signed patient consent form, Real-time PCR, ISO 15189, todylaboratories®, bmn, code L16LD1547

laboratory diagnostic - coagulation - Factor II, Prothrombin, activity, citrated plasma 2ml, The factors II, V, VII, X (prothrombin complex factors) assay requires at least 2 mL of citrate plasma frozen at -20°C. It is advisable to send a frozen and centrifuged citrate sample in compliance with the GEHT pre-analytical recommendations. Attach the clinical data relating to the patient (major inflammatory syndrome, pregnancy, etc.) and the circumstances (bleeding, thrombosis, preoperative evaluation, etc.), The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container, Chronometric method, ISO 15189, todylaboratories®, bmn, code L16LD1545

laboratory diagnostic - coagulation - Factor IX - Antihaemophilic B, activity, citrated plasma 2ml. The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container.The factors VIII, IX, XI,XII (aPTT factors) assay requires at least 2 mL of citrated plasma frozen at -20°C. It is advisable to send a frozen and centrifuged citrate sample in compliance with the GEHT pre-analytical recommendations. Attach the clinical data relating to the patient (major inflammatory syndrome, pregnancy, etc.) and the circumstances (bleeding, thrombosis, preoperative evaluation, etc.), Chronometric, ISO 15189, todylaboratories®, bmn, code L16LD1551

laboratory diagnostic - coagulation - Factor V Leiden - p.Arg506Gln mutation, EDTA whole blood 5ml at ambient temperature or refrigerated if transport time >24 hrs. DO NOT FREEZE!!! ALWAYS attach the medical prescription, clinical data sheet and medical certificate, Real-time PCR, ISO 15189, todylaboratories®, bmn, code L16LD1552

laboratory diagnostic - coagulation - Factor V, Proaccelerin, citrated plasma 2ml, The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container.The factors II, V, VII, X (prothrombin complex factors) assay requires at least 2 mL of citrate plasma frozen at -20°C. It is advisable to send a frozen and centrifuged citrate sample in compliance with the GEHT pre-analytical recommendations. Attach the clinical data relating to the patient (major inflammatory syndrome, pregnancy, etc.) and the circumstances (bleeding, thrombosis, preoperative evaluation, etc.), Chronometric, ISO 15189, todylaboratories®, bmn, code L16LD1553

laboratory diagnostic - coagulation - Factor VII, Proconvertin, citrated plasma 2ml, The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container.The factors II, V, VII, X (prothrombin complex factors) assay requires at least 2 mL of citrate plasma frozen at -20°C. It is advisable to send a frozen and centrifuged citrate sample in compliance with the GEHT pre-analytical recommendations. Attach the clinical data relating to the patient (major inflammatory syndrome, pregnancy, etc.) and the circumstances (bleeding, thrombosis, preoperative evaluation, etc.), Chronometric, ISO 15189, todylaboratories®, bmn, code L16LD1555

laboratory diagnostic - coagulation - Factor VIII, antibodies screening, citrated plasma 2ml, The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container. ALWAYS specify the Factor VIII level. This analysis can only be performed if the factor VIII level is lowered. Attach the clinical data relating to the patient (major inflammatory syndrome, pregnancy, etc.) and the circumstances (bleeding, thrombosis, preoperative evaluation, etc.), Chronometric, ISO 15189, todylaboratories®, bmn, code L16LD1556

laboratory diagnostic - coagulation - Factor VIII, Antihaemophilic A, citrated plasma 2ml, The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container. The factors VIII, IX, XI,XII (aPTT factors) assay requires at least 2 mL of citrated plasma frozen at -20°C. It is advisable to send a frozen and centrifuged citrate sample in compliance with the GEHT pre-analytical recommendations. Attach the clinical data relating to the patient (major inflammatory syndrome, pregnancy, etc.) and the circumstances (bleeding, thrombosis, preoperative evaluation, etc.). Send us the ABO blood group result, Chronometric, ISO 15189, todylaboratories®, bmn, code L16LD1558

laboratory diagnostic - coagulation - Factor Von Willebrand antigen + factor VIII coagulation activity and Ristocetin cofactor activities.Factor Von Willebrand, antigen is performed only if activity is low. citrated plasma 2ml. The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container. Plasma with platelets removed by double centrifugation: 2500 g 15 min. The complete von Willebrand factor assay (von Willebrand factor activity, antigen and factor VIII activity) requires at least 2 x 1 mL citrated plasma tubes frozen at -20°C. Some clinical data relating to the patient (major inflammatory syndrome, pregnancy), the circumstances (bleeding, thrombosis, preoperative evaluation) of the request and ongoing treatments (particularly anti-coagulant treatments and hormone treatments) may influence the results. Therefore, this information is essential for the correct interpretation of cases. The blood group must be known.EIA, ISO 15189, todylaboratories®, bmn, code L16LD1562

laboratory diagnostic - coagulation - Factor X, Anti-Xa activity : low molecular weight heparin - LMWH , citrated plasma 1ml. The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container.ALWAYS specify the current anticoagulant treatment (dosage) and the injection and sampling times. Sample 3 to 4 hours after subcutaneous injection of Lovenox®, Fragmine®, Fraxiparine® , Clivarine® or 4 to 6 hours after subcutaneous injection of Innohep® or Fraxodi® Chronometric, ISO 15189, todylaboratories®, bmn, code L16LD1566

laboratory diagnostic - coagulation - Factor XIII, activity, citrated plasma 1ml. The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container. Chronometric, ISO 15189, todylaboratories®, bmn, code L16LD1569

laboratory diagnostic - coagulation - FDP - fibrinogen and fibrin degradation products, citrated plasma 1ml. The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container. Agglutination, ISO 15189, todylaboratories®, bmn, code L16LD1570

laboratory diagnostic - coagulation - Methylenetetrahydrofolate reductase - MTHFR gene, c.677C>T mutation - thrombophilia risk, EDTA whole blood 5ml at ambient temperature, DO NOT FREEZE!!! Please attach clinical data and signed patient consent form, PCR-RFLP, ISO 15189, todylaboratories®, bmn, code L16LD1571

laboratory diagnostic - coagulation - PAI1, Plasminogen activator inhibitor-1 , citrated plasma 1ml, The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container, Colorimetry, ISO 15189, todylaboratories®, bmn, code L16LD1572

laboratory diagnostic - coagulation - Protein C anticoagulant- activity, citrated plasma 1ml, The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container, Protein C and Protein S assays must be performed at least one month after discontinuing an anti-vitamin K treatment and away (or far) from any thrombotic episode. ALWAYS specify the current anticoagulant treatment. If possible attach the clinical data relating to the patient (major inflammatory syndrome, pregnancy, etc.) and the circumstances (bleeding, thrombosis, preoperative evaluation, etc.), Chromogenic, ISO 15189, todylaboratories®, bmn, code L16LD1576

laboratory diagnostic - coagulation - Protein S free, antigen citrated plasma 1ml, The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container, ALWAYS specify the current anticoagulant treatment. If possible attach the clinical data relating to the patient (major inflammatory syndrome, pregnancy, etc.) and the circumstances (bleeding, thrombosis, preoperative evaluation, etc.), Immuturbidimetry, ISO 15189, todylaboratories®, bmn, code L16LD1579

laboratory diagnostic - coagulation - Protein S, activity citrated plasma 1ml, The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container, ALWAYS specify the current anticoagulant treatment. If possible attach the clinical data relating to the patient (major inflammatory syndrome, pregnancy, etc.) and the circumstances (bleeding, thrombosis, preoperative evaluation, etc.). Protein C and Protein S assays must be performed at least one month after discontinuing an anti-vitamin K treatment and away (or far) from any thrombotic episode, Chronometric, ISO 15189, todylaboratories®, bmn, code L16LD1578

laboratory diagnostic - coagulation - Thrombin clotting time, citrated plasma 1ml, The plasma must be frozen within 1 hour after collection and must be sent in the frozen samples container, ALWAYS specify the current anticoagulant treatment. If possible attach the clinical data relating to the patient (major inflammatory syndrome, pregnancy, etc.) and the circumstances (bleeding, thrombosis, preoperative evaluation, etc.), Chronometric, ISO 15189, todylaboratories®, bmn, code L16LD1584